近日,在DDW2012上,複旦大學附屬中山醫院普外科主任醫師,副教授,內鏡中心副主任周平紅就胃腸道病變的內鏡微創和外科手術治療做了精彩演講。本研究主要評估經口內鏡肌切開術治療賁門失弛緩症的療效和可行性。
編者按:近日,在DDW2012上,複旦大學附屬中山醫院普外科主任醫師,副教授,內鏡中心副主任周平紅就胃腸道病變的內鏡微創和外科手術治療做了精彩演講。本研究主要評估經口內鏡肌切開術治療賁門失弛緩症的療效和可行性。
周平紅教授做主題演講
Peroral endoscopic myotomy (POEM) for esophageal achalasia: 205 cases report
Zhou, Ping-Hong; Yao, Liqing; Zhang, Yi-Qun; Cai, MingYan; Zhong, Yun-Shi; Ren, Zhong; Xu, Mei-Dong; Chen, Wei-Feng; Li, Quan-Lin; Qin, Xin-Yu
Objective: To evaluate the efficacy and the fesibility of peroral endoscopic myotomy (POEM) for esophageal achalasia (AC).
Patients and methods: The clinical data of 205 patients diagnosed as AC and received POEM were reviewed retrospectively in our center during August 2010 and October 2011. The key procedures of POEM were as following, 1) esophageal mucosal incision, 2) submucosal “tunnelling” by endoscopic submucosal dissection (ESD) technique, 3) endoscopic myotomy of the circular muscle, 4) closure of mucosal entry by hemostatic clips.
Results: The average age was 43.9 years (range 6-75), and the average duration of symptoms were 8.7 years (range 3m-50y). 202 patients received POEM successfully (98.5%). POEM procedure failed in 3 patients because of severe submucosal fibrosis due to other previous therapies. The mean operation time was 68.5 min (range 10 – 180) with a mean submucosal tunnelling length of 10.5 cm (range 8-15). The average length of endoscopic myotomy of inner circular muscle was 9.5 cm (range 7-13). No serious complicatios related to POEM were encountered. Dysphagia symptom was relieved significantly during the follow-up period in 199 patients. The mean follow-up period was 8.5 m (range 1-14).
Conclusion: As a new minimally invasive therapy for AC, POEM seems to be very effective to relieve patient’s dysphagia symptom in a short period. Further observations and long follow-up are needed to evaluate long-term outcome and complications.
(複旦大學附屬中山醫院普外科主任醫師,副教授,內鏡中心副主任 周平紅)
專題鏈接:2012美國消化疾病周專題
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