Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone®醫學論壇網-網聚醫學的力量

Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone

作者：Zhaohui Tong, MD; Huaping Dai, MD; Baomin Chen; Ziad Abdoh, MD; Josune Guzman, MD; and Ulrich Costabel, MD, FCCP 來源：醫學論壇網日期：2017-12-11

導讀

Study objectives: Pentoxifylline (POF) has been shown to suppress the cytokine production from lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages (AMs). Sarcoidosis is a granulomatous disease that is driven by the action of tumor necrosis

Study objectives:pentoxifylline(POF) has been shown to suppress thecytokine productionfrom lipopolysaccharide (LPS)-stimulated monocytes/alveolar macrophages(AMs).sarcoidosisis a granulomatous disease that is driven by the action of tumor necrosis factor (TNF)- and other proinflammatory cytokines. In this study, we aimed to investigate the effects of POF on the production of TNF-, interleukin (IL)-1, IL-6, IL-8, IL-10, and the soluble TNF receptors (sTNFRs) 1 and 2 from AMs in sarcoidosis, and we also compared them with those of dexamethasone (DEX).

閱讀全文請見：Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone

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Inhibition of Cytokine Release From Alveolar Macrophages in Pulmonary Sarcoidosis by Pentoxifylline*Comparison With Dexamethasone

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